Semi Prep HPLC Column, RP C4, 5um, 100A. 10mm ID x 50mm Length. Cogent Brand. 1 EA. Special Order Item.
Additional Information:
Cogent RP C4™ is a reversed-phase HPLC stationary phase designed for the purification and isolation of hydrophobic and neutral compounds. Manufactured using a four-carbon butyl ligand bonded to ultra-high purity silica and fully double end capped, this stationary phase provides reproducible chromatographic performance and lower hydrophobic retention than C8 phases. The chemistry is particularly useful for semi-preparative applications where compound recovery, increased loading capacity, and rapid purification are important.
68504-SP50 is a semi-preparative HPLC column packed with 5 µm RP C4™ particles featuring a 100 Å pore size in a 10 mm ID x 50 mm format. The 10 mm internal diameter provides substantially greater sample loading capacity than analytical columns, while the shorter 50 mm length is optimized for faster separations and higher throughput. Typical operating flow rates are approximately 4–8 mL/min depending on mobile phase composition, analyte properties, and system capabilities.
This column is particularly useful for purification of hydrophobic and neutral compounds in pharmaceutical, chemical, and research laboratories. Compared to C8 and C18 phases, the C4 bonded phase provides lower retention, which can improve recovery and reduce purification cycle times. The short 50 mm format is ideal for rapid purification workflows and high-throughput fraction collection. A semi-preparative HPLC system capable of the required flow rates is recommended for optimal performance.
Key Benefits
RP C4™ stationary phase
USP L26 equivalent chemistry
Butyl (C4) bonded phase
Fully double end capped
Ultra-high purity silica support
Lower retention than C8 phases
Increased sample loading capacity
Excellent for compound purification
5 µm particle size
Optimized for high-throughput semi-preparative HPLC
Typical Applications
Semi-preparative HPLC
Compound purification
Fraction collection
Pharmaceutical purification
Hydrophobic compound purification
Neutral compound purification
Method development
Process development
Research and development
Sample isolation
Specifications
Product Type: Semi-Preparative HPLC Column
Stationary Phase: RP C4™
USP Classification: L26
Chromatography Mode: Reversed Phase
Bonded Phase: Butyl (C4)
Endcapping: Fully Double End Capped
Particle Size: 5 µm
Pore Size: 100 Å
Column Dimensions: 10 mm ID x 50 mm
Length: 50 mm
Typical Flow Rate: 4–8 mL/min
Brand: Cogent
Special Order Item Information
Important Notes
Designed for purification of hydrophobic and neutral compounds
Provides less retention than C8 stationary phases
Ideal for semi-preparative purification and fraction collection
The 10 mm ID format offers increased loading capacity compared to analytical columns
Typical operating flow rates are approximately 4–8 mL/min
5 µm particles provide lower operating backpressure and robust performance
Fully double end capped to minimize secondary interactions
The 50 mm length is ideal for rapid purification cycles and high-throughput operation
Requires an HPLC system capable of semi-preparative flow rates
This is a Special Order Item